20
Mar
The treatment of high-dose chemotherapy with autologous bone marrow transplant had serious side effects for the patient including cardiac toxicity sepsis. High-dose chemotherapy also has been associated with risks including severe mucositis myeloablation-causing transfusion dependency and prolonged neutropenia.
Anemia low red blood cell counts Nausea and vomiting.
High dose chemotherapy risks. Low blood cell counts with fatigue and increased risk of infection and bleeding Nausea and vomiting. High-dose chemotherapy also has been associated with risks including severe mucositis myeloablation-causing transfusion dependency and prolonged neutropenia. High-Dose Chemotherapy in Poor-Risk Germ-Cell Tumors.
Testicular cancer is a highly curable cancer. However 30 of patients are refractory to standard therapy and will need additional therapy. This article focuses on the use of high-dose chemotherapy in germ-cell tumors.
Here are some of the more common side effects caused by chemotherapy. Easy bruising and bleeding. Anemia low red blood cell counts Nausea and vomiting.
Mouth tongue and throat problems such as sores and pain. During high-dose chemotherapy the patient receives high doses of chemotherapy and possibly radiation therapy in order to kill the cancer cells. While chemotherapy affects the cancer cells normal cells also may be affected side effects.
The major side effect is bone marrow damage which causes low. High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma. Results of Euro-EWING99 and Ewing-2008.
Purpose For over 30 years the place of consolidation high-dose chemotherapy in Ewing sarcoma ES has been controversial. A randomized study was conducted to determine whether consolidation high-dose chemotherapy improved survival in patients with localized ES at high risk. Certain chemo drugs can damage cells in your heart.
Chemotherapy may also increase your odds of having heart problems such as. Oral complications caused by chemotherapy include the following. Inflammation and ulcers of the mucous membranes in the stomach or intestines.
Easy bleeding in the mouth. The toxic effects of high-dose chemotherapy were primarily myelosuppression mucositis nausea vomiting dehydration peripheral neuropathy and otologic abnormalities. 8 There were three sudden.
This study aims to explore prognostic factors for high-risk neuroblastoma patients with response failure to tandem high-dose chemotherapy and autologous stem cell transplantation HDCTauto-SCT. Survival outcomes were compared according to characteristics at initial diagnosis at relapseprogression and after relapseprogression in patients who experienced. At a median follow-up of 55 months the rate of congestive heart failure was 1 in both the IDD chemotherapy group and the control group which is consistent with the reported incidence associated with epirubicin-based adjuvant chemotherapy.
14 In summary we do believe that the increased toxicities and risks associated with IDD chemotherapy are reasonable in light of the expected benefits in high-risk. The efficacy of high-dose chemotherapy with progenitor-cell rescue for women with breast cancer is a controversial issue. Although historically controlled trials have suggested a survival advantage for high-dose chemotherapy several randomised studies have yet to confirm this advantage.
Two studies however by Bezwoda of patients with high-risk and metastatic disease seemed to show a significant survival advantage for high-dose compared with conventional-dose chemotherapy. Background The use of high-dose adjuvant chemotherapy for high-risk primary breast cancer is controversial. We studied its efficacy in patients with 4.
These acute side effects including nausea vomiting and fatigue can usually be managed with medications and lifestyle changes. Other side effects may include kidney hearing and nerve issues but less than one in 20 patients require inpatient treatment because of good supportive care programs for combination chemotherapy side effects. As the majority of testicular cancer patients are between the.
The treatment of high-dose chemotherapy with autologous bone marrow transplant had serious side effects for the patient including cardiac toxicity sepsis.