11
Nov
These tests can only detect recent exposures to benzene. In addition infection allergies and some drugs may raise the white cell count.
Long-term exposure to excessive levels of benzene in the air causes leukemia a potentially fatal cancer of the blood-forming organs.
Benzene levels in blood. Levels were determined by a modification of USEPA method TO-15 which uses gas chromatographymass spectrometry. The minimal detectable level for benzene is 0014. Immediate signs and symptoms of exposure to benzene.
People who breathe in high levels of benzene may develop the following signs and symptoms within minutes to several hours. Rapid or irregular heartbeat. Death at very high levels Eating foods or drinking beverages containing high levels of benzene.
Chronic inhalation of certain levels of benzene causes disorders in the blood in humans. Benzene specifically affects bone marrow the tissues that produce blood cells. Aplastic anemia a risk factor for acute nonlymphocytic leukemia excessive bleeding and damage to the immune system by changes in blood levels of antibodies and loss of white blood cells may develop.
Benzene can be measured in the blood or breath and breakdown products of benzene can be measured in the urine. These tests can only detect recent exposures to benzene. They cannot predict possible health effects.
Benzene C 6 H 6 is a highly flammable colorless liquid that evaporates quickly into the air. It is harmful to the eyes skin airway nervous system and lungs. Benzene can cause blood cancers like leukemia.
Workers may be harmed from exposure to benzene. The mean blood benzene level in the exposed workers was 33 μgl range 07136 μg1. Phenol proved to be an inadequate monitoring parameter within the exposure ranges investigated.
The muconic and S -phenylmercapturic acid concentrations in urine showed a marked increase during the work shift. The normal total white blood count is approximately 7200mm 3 plus or minus 3000. For cigarette smokers the white count may be higher and the upper range may be 2000 cells higher than normal for the laboratory.
In addition infection allergies and some drugs may raise the white cell count. Table 2 gives the main statistical parameters of blood benzene concentrations in the 150 workers. Each group is also divided on the basis of smoking status.
The median blood benzene concentration of all workers was 251 ngl at the end of the work shift and 174 ngl the following morning with a statistically significant difference W9520. Industrial discharge landfill leachate and disposal of benzene-containing waste are also sources of exposure. Benzene has been detected at high levels in indoor air.
Although some of this exposure might be from building materials paints adhesives etc most is from cigarette smoke in both. Human and animal blood. Calculated benzene bloodair PC normalized to 14 gdL of hemoglobin.
Benzene exposure level of 00 80 or 400 ppm. For the liquid samples. The average smoker 32 cigarettes per day takes in about 18 milligrams mg of benzene per day.
This amount is about 10 times the average daily intake of benzene by nonsmokers. Measured levels of benzene in outdoor air have ranged from 002 to 34 parts of benzene per billion parts of air ppb 1 ppb is 1000 times less than 1 ppm. There is no safe exposure level.
Even tiny amounts can cause harm. The US Department of Health and Human Services DHHS classifies benzene as a human carcinogen. Long-term exposure to excessive levels of benzene in the air causes leukemia a potentially fatal cancer of the blood-forming organs.
Benzene Blood 18900. This blood test is used to monitor exposure to benzene. Benzene is an organic compound that is found in nature and is also manmade.
Natural sources of benzene are volcanoes and forest fires. In 2015 to 2016 the 95th percentile for blood concentration of benzene among persons aged 20 years and older was 03 ngmL. Determinations of benzene concentration in blood and of phenol in urine were made by head-space gas chromatography techniques on samples taken near the end of the work day from two groups of workers potentially exposed to low levels of benzene in the work-place atmosphere.
Experts have known for years that high levels of benzene reduce white blood cell counts and cause leukemia in people. Benzene is found in gasoline and tobacco and is. Benzene is a well-known haematological toxin causing aplastic anaemia and leukaemia.
Some recent studies have shown that low-level benzene exposure. However other studies showed inconsistent results. OSHA set the daily maximum safe level at 1 parts-per-million or 1 ppm.
That means 1 part benzene for every 1 million parts of air over the course of an 8-hour day. The short term exposure limit is 5 ppm for any 15-minute period. Environmental Protection Agency sets the maximum benzene level in drinking water at 5 ppm.