The remaining β-actin signal in unfractionated thymocytes is consistent with the caveat that the majority of T cells in the thymus have only recently begun to express CD4 and thus have not had sufficient time for complete β-actin turnover. Actin cytoplasmic 1 Beta-actin ACTB_HUMAN.
Cell Signaling Technologys β-Actin 8H10D10 Mouse mAb is a Mouse monoclonal antibody clone 8H10D10.
B actin cell signaling. Anzeige Ensure Credible Reproducible Results With CSTs Validated Antibodies Assays. These actin isoforms regulate the contractile potential of muscle cells 1. Actin exists mainly as a fibrous polymer F-actin.
In response to cytoskeletal reorganizing signals during processes such as cytokinesis endocytosis or stress cofilin promotes fragmentation and depolymerization of F-actin resulting in an increase in the monomeric globular form G-actin 3. This Cell Signaling Technology CST antibody is conjugated to the carbohydrate groups of horseradish peroxidase HRP via its amine groups. The HRP conjugated antibody is expected to exhibit the same species cross-reactivity as the unconjugated antibody β-Actin 13E5 Rabbit mAb 4970.
Resting B cells in circulation are activated in a clonally specific fashion through a two-stage signal. The initial signal is generated by the binding of cognate antigen to the B-cell antigen receptor BCR which leads to signaling cascades in the cytoplasm 1. β-Actin 13E5 Rabbit mAb detects endogenous levels of total β-actin protein.
Depsite the high sequence identity between the cytoplasmic actin isoforms β-actin and cytoplasmic γ-actin β-Actin 13E5 Rabbit mAb 4970 does not cross-react with cytoplasmic γ-actin or any other actin isoforms. The transcriptional response of b-actin to extra-cellular stimuli is a paradigm for transcription factor complex assembly and regulation. Serum induction leads to a precisely timed pulse of b-actin transcrip-tion in the cell population.
Actin protein is proposed to be involved in this response but it is not known. The actin cytoskeleton is a dynamic cellular network known for its function in cell morphology and motility. Recent studies using high resolution and real time imaging techniques have revealed that actin plays a critical role in signal transduction primarily by modulating the dynamics and organization of membrane-associated receptors and signaling molecules.
Cell Signaling Technologys β-Actin 8H10D10 Mouse mAb is a Mouse monoclonal antibody clone 8H10D10. The β-Actin 8H10D10 Mouse mAb Antibody was generated using Beta-Actin Actin beta and Actb as the antigen. β-Actin 8H10D10 Mouse mAb detects endogenous levels of total β-actin protein.
β-Actin Antibody 可检测 β-肌动蛋白的内源水平由于肌动蛋白同工型之间的高序列标识β-肌动蛋白抗体可与其他肌动蛋白同工型发生交叉反应 物种反应性 人 小鼠 大鼠 仓鼠 猴 貂 黑腹果蝇 斑马鱼 牛. The remaining β-actin signal in unfractionated thymocytes is consistent with the caveat that the majority of T cells in the thymus have only recently begun to express CD4 and thus have not had sufficient time for complete β-actin turnover. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human β-actin protein.
Actin cytoplasmic 1 Beta-actin ACTB_HUMAN. P60709 Q75MN2 Q96B34 Q96HG5. Supplier also known as.
Anzeige Ensure Credible Reproducible Results With CSTs Validated Antibodies Assays.